LYCIS
Oral sol. 1000mg/5ml (metformin)
BT x BOTTLE x 300ml + (1 syringe x 5ml graduated 0,25ml) + (1 syringe/bottle adaptor) +
(1 x 10ml dosing overcup graduated 5ml,10ml)
LYCIS contains the active substance metformin hydrochloride, which is a biguanide with anti-hyperglycemic effects.
The origin of metformin is found in the plant Galega Officinalis, which has been used traditionally in the folk medicine and which is rich in biguanides.
Biguanide derivatives were traditionally used in the 1920s and 1930s in the treatment of diabetes mellitus but were eventually abandoned mainly due to the advent of insulin.
During the 100 years that came along after its discovery, metformin has erased an adventurous path: it was synthesized in 1920, then put aside for 20 years, brought back to the foreground in 1940 and examined as an active drug in the treatment of malaria. Further research investigations followed by the French doctor Jean Sterne, whose research work in the ‘50s focused on metformin’s effectiveness in the management of diabetes and ultimately led into the approval of metformin in the treatment of diabetes mellitus in France and the United Kingdom in 1957. It took though 37 years for metformin to be approved by the FDA in the USA. Upon its approval, numerous research and clinical studies established it as the most prescribed drug, for oral administration, in the management of type 2 diabetes, while it seems to have a multi-faceted beneficial effect on other functions of the body.
In clinical studies the use of metformin hydrochloride has been associated with the maintenance, or even a slight decrease in body weight, and it also has a beneficial effect on lipid metabolism.
Furthermore, it is included in the World Health Organization‘s List of Essential Medicines, the most safe and effective medicines in a health system.
LYCIS oral solution is indicated for the treatment of type 2 diabetes mellitus, especially in overweight patients, when treatment through appropriate diet and exercise alone does not result in adequate glycemic control.
LYCIS oral solution can be used as monotherapy or in combination with insulin in children 10 years of age and older as well as adolescents.
